Yes, amoxicillin can be used to treat canine interdigital dermatitis. In addition to oral medication, it is also recommended that owners use a pet-specific skin spray such as Miao Shou Yi Sheng (a brand name of pet skin spray). Amoxicillin can be an effective part of a treatment plan for canine interdigital dermatitis. This condition, commonly known as inflammation between the toes, can cause significant discomfort for your dog. Treatment Approaches for Canine Interdigital Dermatitis Besides administering oral antibiotics such as amoxicillin-clavulanate potassium, if your dog’s interdigital skin shows redness, it is advisable to use a pet-specific topical antimicrobial and anti-inflammatory medication. Apply this twice daily for 3-5 consecutive days. During treatment, it's essential to have your dog wear an Elizabethan collar to prevent them from licking the affected area, which can worsen the infection. The Miao Shou Yi Sheng pet skin spray is considered to be quite effective. It ...